Pablo Perez Pinera

Pablo Perez Pinera is an Associate Professor in the Department of Bioengineering at the University of Illinois, with additional affiliations in Biomedical and Translational Sciences, Molecular and Integrative Physiology, and the Carl R. Woese Institute for Genomic Biology. His work focuses on advancing genome editing technologies, particularly CRISPR-based systems and base editing tools.

Research interests include developing precision gene therapies, optimizing viral vector delivery for in vivo applications, and understanding how chromatin structure influences editing efficiency. Recent contributions highlight the creation of the SPLICER base editing toolbox for therapeutic exon skipping and advancements in protein engineering for next-generation genome editors.

His articles emphasize innovations in genome editing applications, such as reducing Alzheimer’s disease precursors in mice via gene editing. Collaborations span interdisciplinary teams addressing biomedical challenges through molecular and genetic approaches.