معرفی
Pablo Penaloza-MacMaster, PhD, is an Adjunct Associate Professor in the Department of Microbiology-Immunology at Northwestern University’s Feinberg School of Medicine. His research focuses on T cell and B cell regulation, particularly mechanisms involving immune checkpoints and type I interferons (IFN-I) to enhance vaccine and immunotherapy efficacy. He holds affiliations with the Center for Human Immunobiology, Northwestern University Clinical and Translational Sciences Institute (NUCATS), Robert H. Lurie Comprehensive Cancer Center, and the Robert J. Havey, MD Institute for Global Health.
Dr. Penaloza-MacMaster earned his PhD from Emory University in 2011 and completed postdoctoral training in Virology at Beth Israel Deaconess Medical Center. His work addresses vaccine optimization, viral pathogenesis, and immune system dynamics in chronic infections. Notable contributions include studies on mRNA vaccine improvements, SARS-CoV-2 neuroinvasion mechanisms, and antibody interference in pediatric immunity.
His research has been recognized with the 2020 Avenir NIH Director New Innovator Award from NIDA. Current projects explore strategies to enhance vaccine responses through delayed antibody treatments and understanding viral evolution in nervous system infections.
Dr. Penaloza-MacMaster collaborates with industry via consulting for Thyreos, LLC, while maintaining academic integrity through Northwestern’s conflict-of-interest policies. His lab’s translational work bridges basic immunology with clinical applications in infectious diseases and cancer immunotherapy.
