Orhan Aktas

Prof. Dr. Orhan Aktas is a faculty member at the Department of Neurology, Heinrich-Heine-University Düsseldorf, leading the Molecular Neurology Research group. His work bridges clinical and experimental neuroimmunology.

• Research Focus: Multiple Sclerosis (MS), Neuromyelitis Optica Spectrum Disorders (NMOSD), MOG Antibody-Associated Disorders (MOGAD).
• Labs/Collaborations: Collaborates with the Albrecht group (visual pathway research), Thiology group (redox signaling), and Neuromyelitis Optica Study Group (NEMOS).
• Clinical Work: Specializes in investigator-initiated trials (IITs) and novel therapy strategies for CNS inflammatory diseases.
• Experimental Work: Investigates redox-dependent histone deacetylases (sirtuins), neural progenitor cell homeostasis, and mechanisms of CNS regeneration using experimental autoimmune encephalomyelitis (EAE) models.

Research Trends: His recent publications highlight biomarker development, therapeutic strategies for NMOSD/MOGAD, neurodegeneration mechanisms, and global epidemiology of rare CNS disorders.