Oren Rosenberg

Oren Rosenberg, MD, PhD, is an Associate Adjunct Professor in the Department of Medicine at the University of California San Francisco (UCSF), School of Medicine. He is a physician-scientist whose laboratory focuses on uncovering molecular vulnerabilities in pathogenic bacteria to develop improved therapeutics for life-threatening infections.

His research spans infectious diseases, structural biology, host-pathogen interactions, and molecular imaging. Using advanced techniques such as cryo-EM, CRISPR screening, and PET radiotracer development, his lab investigates pathogens like Mycobacterium tuberculosis and SARS-CoV-2. His work has led to significant insights into bacterial secretion systems, host immune responses, and the design of novel diagnostics and therapeutics.

Dr. Rosenberg’s recent publications reveal a strong trend in leveraging structural biology and systems-level approaches to understand pathogen mechanisms and engineer solutions. His team develops innovative imaging tools, such as fluorine-18-labeled sensors for in vivo bacterial detection, and explores host factors critical for viral infection. His research bridges basic science and translational medicine, aiming to accelerate antibiotic development and improve infection diagnostics.

He has received no explicitly listed scientific awards in the provided text.

Dr. Rosenberg advises PhD and postdoctoral researchers, though specific names are not provided. His lab has secured research grants supporting work in bacterial imaging, CRISPR-based pathogen interrogation, and therapeutic design, as evidenced by publications in top-tier journals. He collaborates extensively with leading scientists across UCSF and beyond.

His laboratory, the Rosenberg Lab, is a hub for interdisciplinary research integrating microbiology, biochemistry, imaging, and computational biology to combat infectious diseases.