Oneil Guthrie

Oneil Guthrie is a Professor in the Department of Communication Sciences and Disorders at Northern Arizona University, within the College of Health and Human Services. His academic work bridges neuroscience, molecular biology, and environmental health, with a central focus on hearing disorders and noise-induced damage.

His research interests include:

• Noise-induced hearing loss and systemic health effects of noise exposure
• Molecular mechanisms of DNA repair in the inner ear
• Cochlear pathophysiology and ototoxicity (e.g., cisplatin, jet fuel)
• Use of animal models to study hearing impairment
• Gene therapy approaches for hereditary deafness

Recent publications reveal a strong trend toward understanding the intersection of environmental stressors and genomic instability in auditory neurons. His work frequently explores how hazardous noise abrogates DNA repair enzymes like structure-specific endonucleases, linking conditions such as xeroderma pigmentosum to hearing loss. Articles span molecular therapy, toxicology, and clinical reviews, indicating a translational and interdisciplinary approach.

Scientific contributions include:

• Comprehensive reviews on gene therapy for familial hearing loss
• Studies on long-term auditory and systemic effects of acute noise
• Exploration of noise stress on mitochondrial and nuclear DNA in the cochlea
• Systemic health reviews connecting noise exposure to broader physiological impacts

Guthrie actively mentors predoctoral students through the NIH-funded Minority Predoctoral Fellowship Program, demonstrating a commitment to training future scientists. While specific grant details are limited, his leadership as Principal Investigator highlights active research support. His scholarly output is extensive, with a high citation count and h-index, reflecting significant influence in the field of auditory neuroscience and environmental ototoxicology.

He is associated with collaborative research networks focused on noise exposure, cochlear biology, and DNA repair mechanisms, contributing to a robust scientific fingerprint in hearing sciences.