Oliver J. Müller

Oliver J. Müller serves as DZHK Professor for Translational Cardiology at Kiel University and holds an attending physician position at the Department of Internal Medicine III, University Hospital Schleswig-Holstein. His research focuses on identifying novel therapeutic targets for cardiovascular diseases including heart failure, cardiomyopathies, peripheral artery disease, Marfan syndrome, and cardio-oncology.

Prof. Müller's laboratory investigates metabolic, inflammatory, and epigenetic mechanisms driving cardiac remodeling under hemodynamic stress or oncological cardiotoxicity. His team develops optimized adeno-associated virus (AAV) vectors for cardiac and vascular gene transfer, bridging preclinical discoveries with clinical applications. As a clinician-scientist, he leads trials in stem cell therapy for vascular disease and anti-inflammatory approaches for heart failure, emphasizing translational impact from bench to bedside.

His publication record demonstrates consistent innovation in cardiovascular gene therapy, with recurring themes in AAV vector engineering, molecular mechanisms of cardiac remodeling, and cardio-oncology applications across diverse models from mice to large animals.

Major recognitions include:

• Research Award “Benny & Co” of the German Muscular Dystrophy Foundation (2017)
• Research Award German Marfan Foundation (2016)
• Poster Award of the European Society of Cardiology (2014)
• Research Award Benny & Co of the German Muscular Dystrophy Foundation (2013)
• Franz-Maximilian-Groedel-Research Award of the German Society of Cardiology (2009)

Prof. Müller directs a DZHK-affiliated laboratory focused on advancing AAV-based therapies toward clinical translation for severe hereditary cardiovascular conditions, maintaining active collaborations within the German Center for Cardiovascular Research network.