Oliver J. Gruß

Prof. Dr. Oliver J. Gruß serves as Professor of Genetics, Head of the Department of Cell Division, and Chairman of the Biology Department at the University of Bonn's Institute of Genetics. His research explores microtubule functions in eukaryotic cytoskeleton dynamics during interphase and mitosis.

Education:

• Diploma in Biochemistry, University of Regensburg (1994)
• Doctorate in Molecular Cell Biology, Ruprecht-Karls-University of Heidelberg (1998)
• Postdoctoral Research, European Molecular Biology Laboratory (EMBL), Heidelberg
• Research Group Leader and Temporary Professor, Center for Molecular Biology, University of Heidelberg
• Professor of Genetics, University of Bonn (since 2015)

Research Interests: His work focuses on microtubule-binding proteins (MAPs) regulating spindle assembly and chromosome segregation during mitosis, alongside SMN complex functions in cellular stress response and spinal muscular atrophy mechanisms. The lab employs super-resolution microscopy, real-time imaging, and biochemical reconstitution in cell-free systems to investigate cytoskeletal organization and RNP homeostasis.

Scientific Awards:

• President of the German Society for Cell Biology (2021)
• Teaching Award of the University of Bonn for curriculum development (2020)
• Golden Microscope Teaching Award from Biology Department (2021)

Grants and Leadership: Currently leads DFG-funded projects on SMN complex condensation in RNP homeostasis (2022-2023) and MTUS1-mediated microtubule bundles (2023), plus Cure SMA Europe research since 2022. Served as DGZ President (2018-2020) and board member (2012-2020).

Laboratory: Directs the Working Group (AG Gruß) at the Institute of Genetics, specializing in cytoskeleton dynamics through advanced microscopy and structural analysis of cell division mechanisms.