Oliver J Rando

Oliver J Rando is a Professor in the Department of Biochemistry and Molecular Biotechnology at UMass Chan Medical School. His research focuses on epigenetic inheritance, chromatin structure, and genomic regulation. He holds an Endowed Chair in Biochemistry and Molecular Biotechnology and leads studies using genomic tools like DNA microarrays and high-throughput sequencing to analyze chromatin dynamics.

His work explores histone modification patterns, nucleosome replacement mechanisms, and non-coding RNA roles in epigenetic transmission. Current projects investigate chromatin's role in yeast stress responses, stem cell pluripotency, and sperm RNA contributions to embryonic development.

Key research questions include:

• How chromatin motifs are established by genomic sequences
• Mechanisms of replication-independent histone exchange
• Function of histone modification crosstalk
• Chromatin's role in filtering cellular signals
• Epigenetic packaging during gametogenesis