معرفی
Noelle Dwyer is an Associate Professor in the Department of Cell Biology at the University of Virginia School of Medicine, focusing on neural development and genetic mechanisms underlying brain structure.
- BA in Biochemistry from Rice University
- PhD in Neuroscience from University of California, San Francisco
- Postdoctoral training in neurodevelopment at The Salk Institute and neurogenetics at Beth Israel Hospital, Boston
Her research investigates:
- Neural Stem Cell Division: Regulation of abscission timing and midbody remnants in cortical development
- Axon Guidance: Cytoskeletal dynamics in neuronal connectivity
- Genetic Links to Disease: How abscission defects cause microcephaly and relate to cancer biology
Publications highlight her work on kinesin proteins (KIF20B/Kif20b), abscission regulation, and p53-dependent apoptosis in neural development, spanning disciplines like neuroscience, genetics, and cell biology.
Her lab employs mouse genetics, cell biology, and genomic approaches to study:
- Cytokinetic defects in cortical stem cells
- Microtubule cross-linking proteins in neuron morphogenesis
- Evolutionary conservation of abscission mechanisms
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