Nikolay Shirokikh

Dr. Nikolay Shirokikh is a Research Fellow at the Australian National University's John Curtin School of Medical Research, where he leads the Shirokikh Group focusing on Protein Biosynthesis and Homeostatic Control. His research examines rapid cellular responses through gene-specific translation analysis using high-throughput RNA/protein methods and computational biology.

Research interests include:

• RNA biology and translational control mechanisms
• Stress response pathways in cancer and neurological disorders
• Computational modeling of protein biosynthesis

Recent publications (2022-2024) demonstrate a focus on RNA modifications, nanopore sequencing, and machine learning applications in transcriptome analysis. Major themes include RNA modification mapping, translational dynamics under stress, and evolutionary conservation of RNA machinery.

Awards:

• The Gordon Ada Early Career Researcher Award (2016)

Supervises PhD students including Shafi Mahmud, Mohammed Muntasir, Agin Ravindran, and Katrina Woodward. Collaborates with the Hannan Group on cancer therapeutics and contributes to the Shine-Dalgarno Centre for RNA Innovation.