معرفی
Nikolay G. Kolev is a Research Scientist in the Department of Epidemiology of Microbial Diseases at the Yale School of Public Health. He earned his PhD in Biochemistry from the University of Notre Dame and completed postdoctoral training at Yale University.
His research focuses on molecular mechanisms governing the development of Trypanosoma brucei, the parasite causing African sleeping sickness. Key interests include RNA metabolism, antigenic variation, gene expression regulation, and transcriptional activation. He collaborates with Dr. Christian Tschudi to study parasite adaptation and host transmission dynamics.
His recent publications highlight advancements in RNA-binding protein functions, transcriptome profiling, and mechanisms of parasitic gene regulation. Trends in his work span parasitology, molecular biology, and RNA biology, with specific subfields like VSG expression, snoRNA biogenesis, and vector-borne transmission.
Scientific Awards
- Molecular, Cellular and Immunoparasitology Scientific Award (2009) from the American Society of Tropical Medicine and Hygiene
Kolev's contributions include methodological innovations in RNA-Seq and RNAi plasmid design, alongside foundational discoveries in Trypanosoma developmental biology. His work bridges molecular parasitology and public health, targeting neglected tropical diseases through mechanistic insights.
