Nicole Rotter

Prof. Nicole Rotter is a Professor at Heidelberg University's Department of Otorhinolaryngology, Head and Neck Surgery, located at the University Hospital Mannheim. Her research focuses on developing 3D culture models to study immuno-oncological interactions in head and neck cancer (HNC). These models include heterotypic spheroids, ex vivo tissue cultures, and bioprinted systems that mimic tumor microenvironments.

• Research emphasizes anti-PD-1/PD-L1 immunotherapy mechanisms and EMT principles.
• Applies 3R principles (reduce, refine, replace animal research) via xeno-free culture systems.
• Goals include clinical translation for drug testing and treatment stratification.

Publications include work on 3D scaffold-based co-culture models (Engelmann et al., Cancers 2020).

No scientific awards listed. No grants or advising roles explicitly stated.