Nathan J. Smischney

Nathan J. Smischney, M.D., M.S., is a critical care physician and researcher at Mayo Clinic Rochester, affiliated with the Department of Anesthesiology and Perioperative Medicine. He holds memberships in the American College of Chest Physicians, Society of Critical Care Medicine, and American Society of Anesthesiologists.

• 2018 M.S. in Clinical and Translational Science, Mayo Graduate School
• 2007 M.D., University of Minnesota Medical School

His research focuses on optimizing sedation and hemodynamic stability in critical care, particularly through ketamine/propofol admixture ("Ketofol") for endotracheal intubation. Clinical trials and case series demonstrate his work on comparing Ketofol with etomidate and evaluating its resuscitation properties.

Key publications analyze Ketofol's hemodynamic effects in ICU settings (2022), compare its efficacy with etomidate (2015, 2019), and document its adoption trends (2015). His work bridges pharmacology and clinical practice in acute care environments.

• 2023 Presidential Citation, Society of Critical Care Medicine
• 2011 Excellence in Research Award, Dartmouth-Hitchcock
• 2003 Summa Cum Laude Graduate, University of Minnesota

Dr. Smischney actively participates in quality improvement initiatives and serves on professional committees related to medication safety and critical care education. His clinical expertise spans renoprotection, hypertonic saline resuscitation, and hemodynamic alterations during intubation.