معرفی
Dr. Natalie Tatum is a researcher affiliated with Newcastle University, specializing in structural biology and drug discovery. Her work focuses on elucidating molecular mechanisms of protein complexes, RNA helicases, and DNA repair pathways, with applications in cancer therapeutics and infectious diseases.
Research Interests
- Structural analysis of CDK-cyclin complexes and their regulatory roles in cell cycle
- Targeting SARS-CoV-2 helicase for antiviral drug development
- Structure-based cancer drug discovery using fragment screening and molecular modeling
- Exploiting synthetic lethality in epithelial ovarian cancers
Key Collaborations
She collaborates with Professor Martin Noble, Professor Jane Endicott, and other structural biologists on interdisciplinary projects spanning computational modeling, cryo-EM, and biochemical validation.
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