معرفی
Natalie Grima is a Postdoctoral Research Fellow in the Genomics and Bioinformatics Team at Macquarie University's Motor Neuron Disease Research Centre. She holds a PhD from Macquarie University (2025) and a BSc (Advanced) (Honours I) from the University of Sydney (2017). Her research focuses on the molecular basis of sporadic amyotrophic lateral sclerosis (ALS), leveraging genomic and transcriptomic techniques. Current projects include characterizing the MND brain transcriptome via RNA sequencing and investigating genetic variants associated with neurodegenerative diseases.
Education: PhD in Genomics (Macquarie University, 2025), BSc Advanced (Biochemistry/Immunology, University of Sydney, 2017). External positions include a 3-month Research Residency at the University of Graz (2023).
Research interests span ALS pathogenesis, transcriptomic profiling, and neurodegenerative biomarker discovery. Her work has led to insights into RNA alterations in ALS, molecular subtypes via peripheral blood analysis, and genetic landscape mapping through over 1,000 variants. Key projects include FightMND-funded initiatives on gene therapies, TDP-43 regulation, and genomic/transcriptomic features of sporadic MND.
Notable awards include the 2024 ISMND Travel Fellowship and Society for Neuroscience Professional Development Award. She has been principal or co-investigator on grants totaling $1.2M+, including FightMND and MNDRA scholarships.
Labs/teams: Genomics and Bioinformatics Team (MND Research Centre), collaborating with international groups on ALS-Frontotemporal Dementia links and neurodegenerative biomarkers. Active in biobank development and omics methodology innovations.
