معرفی
Natalie Goto is an Associate Professor in the Department of Chemistry and Biomolecular Sciences at the University of Ottawa, Faculty of Science. Her research focuses on understanding protein structure-function relationships using solution NMR spectroscopy, particularly in membrane-associated proteins and their dynamic interactions with cellular membranes. Key areas include cell signaling, viral infection mechanisms, and cell division regulation.
Education and Background: Dr. Goto’s expertise lies in biophysical chemistry and membrane protein structural biology. Her lab develops novel NMR methodologies to study challenging membrane protein systems.
Research Interests: Protein dynamics, membrane protein structure determination, detergent effects on protein stability, and functional implications of protein-membrane interactions. Current projects investigate MinE’s role in bacterial cell division and Ff bacteriophage coat proteins.
Publications Overview: Her work spans 20+ years, with recent contributions in protein computational design, enzyme conformational landscapes, and PCSK9-LDL binding mechanisms. Themes include integrating experimental and computational approaches to study protein function.
Awards: No awards explicitly mentioned in provided texts.
Advising and Labs: While specific student names aren’t listed, her lab actively explores structural biology challenges using NMR. No grants or funding details provided in current data.
Lab Focus: The Goto Lab specializes in structural and biophysical studies of proteins in membrane environments, emphasizing methodological innovation for membrane protein analysis.
