معرفی
Prof. Dr. N.C. van de Merbel is an Honorary Professor in Industrial Bioanalysis at the University of Groningen's Faculty of Science and Engineering, affiliated with the Analytical Biochemistry department within the Groningen Research Institute of Pharmacy. He also serves as Scientific Director at PRA International's bioanalytical laboratory. His research focuses on mass spectrometry, liquid chromatography, and regulated bioanalysis, with expertise in developing advanced analytical methods for pharmaceutical and biomedical applications.
His work spans bioanalysis of therapeutic proteins, drug metabolism, and biomarker detection, utilizing cutting-edge techniques like LC-MS/MS. Recent studies include investigations into hormone regulation (e.g., SHBG and growth hormone isoforms), protein stability (e.g., trastuzumab and pertuzumab), and antibody-drug interactions. His contributions bridge fundamental research and clinical/industrial applications, emphasizing method development for accurate quantification and characterization of biomolecules.
Prof. van de Merbel collaborates extensively in drug development and regulatory science, addressing challenges in bioanalytical methodologies. His lab supports preclinical and clinical studies, ensuring robust analytical platforms for biopharmaceuticals and biomarkers.
