Mypinder Sekhon

Dr. Mypinder Sekhon is a Clinical Assistant Professor (full-time faculty) in the Department of Medicine at the University of British Columbia. He practices as an intensive care physician at Vancouver General Hospital, where he works in a 34-bed mixed medical surgical ICU that provides quaternary neurocritical care for the province of British Columbia.

Dr. Sekhon is currently completing his PhD in neurophysiology with a thesis focused on investigating the pathophysiology of hypoxic ischemic brain injury after cardiac arrest. His research integrates critical care medicine with advanced neurophysiological monitoring techniques to improve outcomes in patients with severe brain injuries.

Research Interests

Dr. Sekhon's primary research interests center on neurocritical care and hypoxic ischemic brain injury following cardiac arrest. His work investigates cerebral autoregulation, optimal mean arterial pressure targets, and the pathophysiological mechanisms underlying brain injury after cardiac arrest. He has made significant contributions to understanding the relationship between systemic hemodynamics and cerebral oxygenation in critically ill patients.

His research program bridges critical care physiology and neuroscience, with particular focus on how cerebral perfusion can be optimized in patients with traumatic brain injury and post-cardiac arrest syndrome. Dr. Sekhon has pioneered work using near-infrared spectroscopy to assess cerebral autoregulation and determine optimal blood pressure targets for individual patients.

Publication Trends

Dr. Sekhon's recent publications (2020-2021) demonstrate a strong focus on neurocritical care applications, particularly in the context of cardiac arrest and traumatic brain injury. A significant portion of his recent work addresses the physiological mechanisms of hypoxic ischemic brain injury, cerebral autoregulation, and optimal hemodynamic management. Notably, several publications examine the intersection of critical care and emerging infectious diseases, with multiple papers investigating the pathophysiology of severe respiratory failure in COVID-19 patients from a neurocritical care perspective.

Scientific Awards

• VCHRI mentored Clinician Scientist Award
• Clinician Scientist Award
• Charles Best CIHR Doctoral Award
• Frederik Banting CIHR Doctoral Award
• Spring 2020 CIHR Project scheme funding

Grants and Research Support

Dr. Sekhon has secured significant research funding through competitive grant mechanisms. His VCHRI mentored Clinician Scientist and Clinician Scientist Awards provided foundational support for his early career. His CIHR Doctoral Awards (Charles Best and Frederik Banting) supported his PhD work in neurophysiology. Most recently, he received operational funding through the Spring 2020 CIHR Project scheme competition for work related to hypoxic ischemic brain injury, demonstrating the ongoing competitiveness and relevance of his research program.

Research Environment

Dr. Sekhon works within the Division of Critical Care Medicine at Vancouver General Hospital, part of a robust neurocritical care research program. His work involves collaboration with the Canadian Critical Care Trials Group and multiple international research teams. He utilizes advanced multimodal neuromonitoring techniques in his research, including near-infrared spectroscopy, transcranial Doppler, and invasive intracranial pressure monitoring to investigate cerebral physiology in critically ill patients.