Mostafa Elfawal
استادیار · Parasitic Nematode Drug Development
University of Massachusetts Chan Medical Schoolمعرفی
Dr. Mostafa Elfawal is an Assistant Professor at UMass Chan Medical School in the Program in Molecular Medicine, affiliated with the T.H. Chan School of Medicine. His research focuses on developing novel therapeutics against parasitic infections, particularly targeting soil-transmitted helminths and malaria. He completed his PhD in Medical Entomology/Microbiology at the University of Massachusetts Amherst, following a BA and MS in Animal Science from Ain Shams University in Egypt.
His work emphasizes high-throughput drug screening and repurposing existing compounds for anthelmintic use, with recent breakthroughs in PIM kinase inhibitors and broad-spectrum antiparasitic agents. He has extensively studied Artemisia annua's antimalarial properties and its role in overcoming drug resistance. Collaborations with institutions like the NIH and international networks highlight his global impact in parasitology and tropical medicine.
Key contributions include identifying metabolic enzyme inhibitors as anthelmintics, elucidating hookworm's cognitive and microbiome effects, and advancing yeast particle encapsulation for controlled drug release. His research bridges basic science with clinical application, addressing critical gaps in treating neglected tropical diseases.
