معرفی
Dr. Mohamed Metwaly is a Lecturer at the Sydney Pharmacy School, University of Sydney, within the Faculty of Medicine and Health. His research focuses on drug discovery, anion transporters, and medicinal chemistry, with particular emphasis on cancer therapeutics, antimicrobial agents, and enzyme inhibition mechanisms. He actively contributes to interdisciplinary initiatives such as The Drug Discovery Initiative, The University of Sydney Nano Institute, and the Charles Perkins Centre.
His research interests include the design of small molecules targeting carbonic anhydrase isoforms, switchable anion receptors for chemotherapy, and novel antimicrobial adjuvants. Current projects involve developing selective carbonic anhydrase inhibitors and exploring stimuli-responsive anion transporters for cancer treatments.
Metwaly’s publications highlight advancements in anion transport mechanisms, anticancer drug design, and enzyme inhibition strategies. Notably, his work on fluorescent transmembrane HCl transporters and platinum-based chloride transporters demonstrates innovations in cancer cell targeting and apoptosis induction. His research bridges chemistry, biology, and pharmacology, addressing unmet clinical needs in oncology and infectious diseases.
He has supervised students like Raed AHMED on projects related to anion transporters. Metwaly’s grants include the 2023 NSW CVRN Research Innovation Grant from the Victor Chang Cardiac Research Institute, supporting cardiovascular research initiatives.
He collaborates with teams at the Sydney Pharmacy School and affiliated institutes, focusing on translational drug discovery and biomedical applications of anion transport systems.
