Ming Lei

Ming Lei is a Professor of Physiology and Pharmacology at the University of Oxford. His research focuses on cardiac electrophysiology, signal transduction, and molecular mechanisms of arrhythmias. He leads the Lei Group, also known as the Cardiac Signalling Group, which explores novel therapeutic targets for cardiovascular diseases.

• Education: BM, MD, D.Phil
• Professional Recognition: Fellow of the Royal Society of Biology (FRSB)

Recent publications highlight his work on:

• PAK Kinases as targets for arrhythmias
• Anti-arrhythmic drug classification and clinical applications
• Isoform-specific glycosylation of ion channels
• Optical mapping techniques in preclinical cardiac models
• Stem cell-derived cardiomyocytes for studying atrial function

His research trends emphasize molecular mechanisms of cardiac dysfunction, kinase modulation, and advanced imaging methodologies. The Lei Group collaborates on projects involving genetic models (e.g., RyR2 knock-in mice) and cellular interactions (e.g., myofibroblast-cardiomyocyte crosstalk). Key subfields include signal transduction, lysosomal pathways, ion channel regulation, cardiac hypertrophy, electrophysiological imaging, and stem cell applications.