معرفی
Professor Mikael Widersten is a faculty member at Uppsala University's Department of Chemistry - BMC, within the Disciplinary Domain of Science and Technology. He holds the position of Professor in Biochemistry (Molecular Catalysis) and leads the Widersten research group focused on enzyme structure-function relationships and biocatalyst development.
His primary research interests include:
- Understanding structure/function relationships in enzymes
- Development of new and useful biocatalysts
- Reactions generating chiral and pro-chiral product molecules
- Protein engineering for improved enzymatic function
- Structural enzymology and enzyme kinetics
Professor Widersten's extensive publication record demonstrates expertise across enzyme engineering, with particular focus on aldolases, dehydrogenases, epoxide hydrolases, and alcohol dehydrogenases. His work integrates structural biology, protein engineering, and enzyme kinetics to develop biocatalysts for asymmetric synthesis applications. The research spans from fundamental enzyme mechanisms to practical applications in organic synthesis and pharmaceutical development.
As Assistant head of department at the Department of Chemistry - BMC, Professor Widersten contributes significantly to academic administration while maintaining an active research program. His leadership role underscores his standing within the department and university.
Professor Widersten supervises PhD students and researchers in the Widersten group, including Eugenia Cornelius Chukwu and Joel Leufstadius, fostering the next generation of biochemists and enzyme engineers through hands-on research mentorship.
