معرفی
Dr. Miguel Pineda is a Lecturer in Molecular Biosciences at the University of Glasgow, focusing on immunology and glycobiology in inflammatory diseases. His research explores the role of synovial fibroblasts in rheumatoid arthritis (RA), emphasizing glycan-mediated cell-cell interactions and helminth-derived immunomodulators like ES-62.
- Medical Research Council Grant (2024-2027): Synovial glycome in inflammation
- Arthritis Research UK Grant (2016-2021): Targeting glycan pathways in RA
Pineda's work reveals how aberrant glycosylation in fibroblasts drives chronic inflammation and how parasitic worm products reset immune homeostasis via microbiome and epigenetic mechanisms. His 2024-2021 studies demonstrate ES-62's microbiome-dependent arthritis protection and metabolic rewiring by propolis extracts.
Recent articles highlight trends in glycan immunobiology, helminth therapeutics, and stromal cell inflammation. Key subfields include synovial fibroblast sialylation, TLR4 signaling in lung injury, and microbiome-bone marrow axis modulation.
- 2024: ES-62 gut-joint axis study
- 2023: CD20⁺ T-cell inflammatory mechanisms
- 2021: Apigenin C-glycosides in lung inflammation
Pineda supervises researchers like Çağlar Çil and Julia Isakova. His grants from MRC, Cancer Research UK, and Arthritis Research UK fund projects on glycan signatures, 3D fibroblast cultures, and immuno-oncology-arthritis intersections. Collaborations span parasitology, immunology, and metabolomics.
