معرفی
Mickaël Puaud is a Researcher in the Department of Psychology at the University of Cambridge. His work focuses on understanding the neurobiological mechanisms underlying addiction, compulsive behaviors, and drug-seeking habits. Puaud’s research integrates behavioral neuroscience, pharmacology, and neuroanatomy to investigate how dopamine pathways, astrocyte function, and environmental factors contribute to addiction vulnerability and relapse.
His studies often utilize animal models to explore the role of brain regions like the striatum, amygdala, and insular cortex in compulsive behaviors. Key themes include the interplay between noradrenergic systems and Pavlovian conditioning, the neuroadaptive changes preceding heroin seeking, and the efficacy of pharmacological interventions like baclofen and N-acetylcysteine in reducing compulsive drug use.
Recent work emphasizes sex-dependent mechanisms in addiction, the impact of stress on coping strategies, and how habitual control over drug-seeking behaviors predicts compulsive outcomes. Puaud’s contributions highlight the importance of both neurochemical modulation and environmental influences in shaping addiction-related behaviors.
