Michelle E. Melisko

Dr. Michelle E. Melisko is a Clinical Professor at the University of California, San Francisco (UCSF) School of Medicine and a practicing medical oncologist specializing in breast cancer care at the UCSF Breast Care Center. With expertise in chemotherapy combinations, biological therapies, and immunotherapies, she focuses particularly on treating breast cancer that has metastasized to the brain.

• Wake Forest University School of Medicine (MD, 1997)
• Stanford Medicine (Internal Medicine Residency, 1998)
• UCSF (Hematology & Oncology Fellowship, 2003)

Her research emphasizes clinical trial innovation, including system-level approaches to boost patient enrollment and digital health implementation for early-stage breast cancer. Recent publications highlight her work in optimizing antibody-drug conjugate sequencing for HER2-low metastatic cases and advancing patient-reported outcome systems in adaptive platform trials. Dr. Melisko actively promotes patient participation in clinical trials as a pathway to accelerated therapeutic breakthroughs.

As a triple board-certified specialist (Medical Oncology, 2003; Hospice & Palliative Medicine, 2012), she combines clinical expertise with compassionate care, as evidenced by her 5.0 patient rating across 145 reviews. Her practice locations include:

• UCSF Breast Care Center - San Francisco (1825 Fourth St., Third Floor)
• UCSF Cancer Center San Mateo (218 DeAnza Blvd.)