Jo Chien

Dr. Jo Chien is Professor of Medicine at the University of California San Francisco (UCSF) and Medical Director of Breast Medical Oncology at the Helen Diller Family Comprehensive Cancer Center. She specializes in breast cancer treatment and translational research, leading clinical trials to optimize therapies.

Education:

• 1994–1998: Stanford University, B.S. Honors in Biology
• 1998–2003: Harvard Medical School, M.D.
• 2003–2006: Massachusetts General Hospital, Internal Medicine Residency
• 2006–2009: UCSF, Hematology/Oncology Fellowship (Chief Fellow 2007–2009)

Research Focus: Dr. Chien develops novel treatments for early-stage/metastatic breast cancer, with emphasis on endocrine optimization, HER2-targeted therapies, and triple-negative subtypes. She leads the I-SPY2 Endocrine Optimization Protocol and founded a registry for young women with breast cancer to study diagnosis/treatment impacts.

Publication Trends: Her recent articles focus on clinical trials (I-SPY2, CONTROL), therapeutic toxicities, HER2-low biology, and survivorship interventions. Key themes include drug combinations, biomarker-driven strategies, and patient-centered outcomes across breast cancer subtypes.

Awards & Honors:

• ASCO Young Investigator Award
• American Cancer Society Postdoctoral Fellowship
• NIH Clinical Research Loan Repayment
• UCSF Teaching Award
• Howard Hughes Research Grant
• Phi Beta Kappa Society Electee

Grants & Leadership: Funded by NIH/NCI, DOD, ASCO, and philanthropic sources. Principal Investigator for multicenter trials; oversees young women’s oncology registry and mentors junior researchers.