Michele ZOLI

Michele ZOLI is a Full Professor in the Department of Biomedical, Metabolic and Neuroscience Sciences at the University of Modena and Reggio Emilia. His academic roles include teaching courses on physiological systems, neurophysiology, clinical medicine, and biomedical engineering. Key research focuses include neurodegenerative diseases (Alzheimer’s, epilepsy), nicotinic receptor biology, and translational neuroscience. He leads studies on synaptic plasticity, neuroinflammation, and drug mechanisms targeting brain pathologies. His work bridges basic science and clinical applications.

Research Interests: Neurophysiology, neurodegeneration mechanisms, nicotinic receptor pharmacology, synaptic dysfunction, and translational therapies. Specific areas include amyloid pathology modulation, neuronal plasticity under stress, and drug development for neurological disorders.

Recent Article Trends: Recent publications emphasize Alzheimer’s pathology (PCSK9’s role in amyloid plaques), nicotinic receptor signaling in epilepsy and cancer, and ketamine’s effects on depression. Studies often use transgenic models (5XFAD mice) and advanced imaging techniques. Research highlights the interplay between molecular pathways and behavioral outcomes.

Teaching Contributions: Courses span molecular physiology, clinical neurophysiology, emergency medicine, and biomedical engineering. He emphasizes quantitative approaches in bioengineering and integrates imaging techniques into teaching. Students engage with computational simulations and clinical case studies.