معرفی
Dr. Michał Rychłowski is a Researcher affiliated with the Intercollegiate Faculty of Biotechnology at the University of Gdańsk and Medical University of Gdańsk, Department of Recombinant Vaccines. His work focuses on biotechnological innovations in cancer biology, virology, and photodynamic therapy, with an emphasis on protein-nanoparticle interactions and cellular mechanisms of disease. Key research areas include molecular chaperones, targeted protein degradation (LYTACs), and drug delivery systems. He explores host-pathogen interactions in skin infections and cancer metastasis, particularly involving Staphylococcus aureus and prostate cancer cell invasiveness.
His studies incorporate advanced techniques like proteomic profiling, in vitro infection models, and light-activated therapies. Notable contributions include gallium porphyrin-based photodynamic approaches against antibiotic-resistant bacteria and mechanistic insights into Hsp70/Hsp110 chaperone networks. Collaborations bridge biotechnology, molecular biology, and clinical applications, aiming to develop novel therapeutic strategies.
Research also addresses podocyte dysfunction in kidney disease, focusing on signaling pathways like AMPK/PKGIα and their roles in albumin permeability under diabetic conditions. His work on extracellular vesicles highlights their dual role in cellular homeostasis and pathogen exploitation. Despite prolific publication output, no formal awards or student advisement records are explicitly mentioned.
