Michael Youssef

Dr. Michael Youssef is a Clinical Assistant Professor in the Department of Neurology at UT Southwestern Medical Center, specializing in neuro-oncology. He focuses on clinical care and research related to brain tumors, including gliomas, meningiomas, and metastatic brain lesions. His work emphasizes improving outcomes through innovative therapies and addressing health disparities in glioblastoma care.

Education:

• Bachelor's in Neuroscience, University of Pittsburgh
• Medical Degree, Medical University of South Carolina
• Neurology Residency, Baylor College of Medicine
• Neuro-Oncology Fellowship, MD Anderson Cancer Center

Research Interests:
Dr. Youssef investigates molecular mechanisms of glioblastoma progression, radiation therapy optimization, and clinical trial design for neuro-oncology patients. His work bridges basic science (e.g., EGFR signaling pathways) with translational research targeting treatment resistance and metastasis. Recent studies explore CSF-based biomarkers for leptomeningeal disease and personalized radiation protocols (PULSAR).

Publications Trends:
Over 20 peer-reviewed articles focus on glioblastoma treatment disparities, novel therapies (e.g., convection-enhanced drug delivery), and neuro-oncology biomarkers. Key themes include molecular profiling of tumors, radiation-induced hematologic changes, and clinical trial methodology improvements.

Honors:

• American Brain Tumor Association Grant (Medical School Research)

Grants & Leadership:
Leads multidisciplinary teams in neuro-oncology clinical trials. Active in institutional leadership at UT Southwestern, contributing to neurology department strategy and residency training.

Labs/Teams:
Affiliated with the Neuro-Oncology Section at UT Southwestern, collaborating with radiation oncology and neurosurgery teams on translational research projects.