Michael Toft Overgaard

Michael Toft Overgaard is a Professor at Aalborg University's Department of Chemistry and Bioscience, affiliated with The Faculty of Engineering and Science. His research focuses on protein science, with particular emphasis on calmodulin mutations linked to cardiac arrhythmias, hibernation physiology in brown bears, and functional peptide characterization.

Key projects include investigations into calmodulinopathy mechanisms (funded by the Danish Cardiovascular Academy) and protein valorization through enzymatic hydrolysis (Novo Nordisk Foundation). Notable contributions include identifying calmodulin mutations' effects on neuronal and cardiac function, and elucidating metabolic adaptations in hibernating bears.

Recent publications (2023-2025) address calmodulin's role in arrhythmias, hibernation endocrinology, and peptide-based emulsifiers. His work impacts forensic genetics, as seen in the re-evaluation of the Australian infanticide case involving calmodulin mutations.

Collaborations span proteomics, cardiovascular research, and wildlife biology, with datasets deposited in PRIDE and Zenodo. Professional activities include external examinations and advisory roles in protein innovation.