معرفی
Michael Selzer is a Professor in the Department of Neural Sciences at the Lewis Katz School of Medicine, Temple University, and holds a concurrent Professorship at the Center for Neural Development and Repair. His clinical focus centers on neurorehabilitation.
Education
- AB, University of Pennsylvania, 1962
- MD/PhD, New York University, 1968
- Internship, New York University Bellview Hospital, 1969
- Fellowship, National Institute of Neurological Disorders and Stroke (NINDS), NIH, 1971
- Residency, Hospital of the University of Pennsylvania, 1974
Research Interests
Dr. Selzer's laboratory investigates fundamental mechanisms of central nervous system regeneration using the sea lamprey spinal cord model. His team pioneered discoveries showing selective axon pathfinding and functional synapse reformation after injury. Current research employs in vivo micro-imaging and two-photon microscopy to analyze intermittent regeneration patterns, neurofilament dynamics, and cAMP-mediated acceleration of axon regrowth. A major focus examines dependence receptor-mediated apoptosis in poorly regenerating neurons following guidance molecule ligand depletion near injury sites.
Scientific Recognition
- Recipient of sustained NIH and federal research funding
- Peer review panel service for NIH, Department of Veterans Affairs, and National Multiple Sclerosis Society
Leadership and Collaborations
As President of the World Federation for Neurorehabilitation, Dr. Selzer shapes global rehabilitation standards. His laboratory collaborates extensively with Dr. Michael Shifman on molecular mechanisms of neuronal survival, maintaining active research programs supported by continuous federal and voluntary organization grants.
Research Infrastructure
His laboratory operates advanced imaging facilities for real-time axon regeneration tracking, featuring two-photon microscopy systems enabling pharmacological and molecular intervention studies in the sea lamprey model.
