Michael Rout

Michael Rout, PhD is a Professor at Rockefeller University, specializing in the study of nuclear pore complexes (NPCs). His research focuses on elucidating the structural and functional mechanisms of NPCs using advanced techniques such as X-ray crystallography, cryo-electron microscopy, and single-molecule methods. He leads the Rout lab, which investigates nucleocytoplasmic transport and nuclear regulation. Dr. Rout's work also contributes to biotechnological advancements through protein engineering and computational chemistry.

Education:

• PhD, 1990, University of Cambridge
• MA, 1990, University of Cambridge
• BS, 1986, University of Cambridge

Research Interests:
Dr. Rout’s lab explores how NPCs facilitate material transport between the nucleus and cytoplasm, their role in genetic regulation, and their interactions with cellular components like nuclear transport factors and the nuclear periphery. Techniques developed in his lab are disseminated via the National Center for Dynamic Interactome Research, which trains researchers in interactomic methodologies.

Labs & Collaborations:
The Rout Lab collaborates widely, leveraging interdisciplinary approaches to advance understanding of cellular systems. The National Center for Dynamic Interactome Research, co-founded by Rout, serves as a hub for training and disseminating cutting-edge interactomic tools.