
معرفی
Dr. Michael R. Williams is an Assistant Professor in the Department of Pediatrics and Human Development at the Michigan State University College of Human Medicine. His research focuses on identifying therapeutic targets for neurodevelopmental disorders by studying autism spectrum disorder (ASD) candidate genes and their roles in neuronal development. He leads the Williams Lab, which uses viral and transgenic strategies to model genetic mutations in murine neurons, combining biochemistry, electrophysiology, and behavioral assays.
Education:
- BS in Neuroscience, St. Lawrence University (USA)
- PhD in Neuroscience, University of Vermont (USA)
- Postdoctoral Research at Dartmouth College (Luikart Lab)
Research Interests:
Dr. Williams investigates how genetic mutations (e.g., in PTEN and KIT genes) disrupt neuronal migration, synaptogenesis, and synaptic function, contributing to ASD and comorbid conditions like epilepsy. His lab specializes in creating animal and cellular models to dissect the causal biology of these mutations.
Funding & Recognition:
- NIH/NIMH K99/R00 Grant (2016–2019)
- NIH/NIMH L40 Grant (2015–2018)
- LRP Ambassador (NIH, 2018)
- Young Investigator Travel Award (2016)
Collaborations & Training:
Dr. Williams collaborates on neurodevelopmental disorder research and provides expertise in viral/plasmid model generation. His lab offers training in advanced molecular neuroscience techniques, including CRISPR-Cas9 systems and in vivo neuronal manipulation.
Labs/Teams:
The Williams Lab actively seeks partnerships to expand studies on PI3K/Akt/mTOR pathways and other ASD-related mechanisms.
Michael R. Williams در جاهای دیگر
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