معرفی
Michael Hastings is a Research Leader at the MRC Laboratory of Molecular Biology, University of Cambridge, where he investigates the molecular neurobiology of circadian rhythms. His work focuses on the suprachiasmatic nucleus (SCN) as the central circadian pacemaker in mammals, utilizing advanced techniques including real-time in vivo imaging, genomics, and molecular genetics to dissect clock mechanisms.
Research Interests: Dr. Hastings explores how clock genes and proteins assemble into functional oscillators, how astrocytes and neurons interact to sustain circadian rhythms, and how central/peripheral clocks coordinate physiological processes. His group also studies evolutionary conservation of timing mechanisms in marine organisms.
Publication Trends (2022-2025): Recent articles emphasize astrocyte-mediated regulation of SCN circuitry, dynamic protein behavior (e.g., PER2, CRY1), and genomic/environmental control of circadian timing. Key themes include glial-neuronal crosstalk, molecular switches for clock resetting, and multi-omic approaches to network-level timing.
Research Team: Current group members include Elena del Carmen Gómez García, Olivia Johnson, Andrew Oliphant, Andrew Patton, Chee Sia, and Nicola Smyllie.
