معرفی
Michael G DeCuypere, MD, PhD, serves as Associate Professor in Neurological Surgery at Northwestern University's Feinberg School of Medicine and Director of Translational Research and Clinical Trials in Pediatric Neurosurgery at Lurie Children's Hospital of Chicago. Joined in 2021, he specializes in advancing pediatric brain tumor treatment through innovative clinical trials and minimally invasive surgical techniques within the multidisciplinary pediatric brain tumor program.
His educational background includes:
- BS: Tennessee Technological University (2002)
- PhD: University of Tennessee Neuroscience Institute (2009)
- MD: University of Tennessee Health Science Center College of Medicine (2010)
Postgraduate training comprised Neurological Surgery residency at University of Tennessee/Semmes-Murphey Institute (2016), followed by fellowships in Minimally Invasive Neurosurgical Oncology (2016) and Pediatric Neurosurgery at St. Jude Children's Research Hospital (2017).
Dr. DeCuypere's research centers on translational neuro-oncology, with emphasis on molecular characterization of pediatric gliomas and immune-based therapeutic development. His work bridges basic science discoveries to clinical applications through precision medicine approaches, focusing on histone mutations (H3 K27/H3.3-G34R), epigenetic reprogramming, and novel immunotherapies for diffuse midline and hemispheric gliomas.
Recent publications (2024-2025) demonstrate consistent focus on tumor molecular profiling, therapeutic efficacy enhancement, and health disparity analysis in pediatric CNS tumors, reflecting his commitment to developing targeted clinical trial interventions.
Key recognition includes:
- Eleanor Clarke Research Scholar in Developmental Neurobiology (2021)
As Director of Translational Research, he leads clinical trial development and collaborates extensively with Lurie Children's neuro-oncology program. His editorial roles include Journal of Clinical Neuroscience (2023-present) and Cancers (2022-present), while professional memberships span ASPN, SNO, AANS, and CNS.
Dr. DeCuypere directs translational research initiatives within Pediatric Neurosurgery, coordinating with the Center for Cancer & Blood Disorders to establish Lurie Children's as a national hub for pediatric brain tumor research through molecularly targeted clinical trials and immunotherapy development.
