Michael Fried

Michael Fried, Ph.D., is a Professor in Molecular and Cellular Biochemistry, with affiliations to the Center for Structural Biology, Markey Cancer Center, and the Molecular and Cellular Oncology Research Program. His career spans decades, including roles at institutions like the Van Andel Institute (PI, 2022–2023) and collaborations with the University of North Carolina Chapel Hill (CoI, 2012–2014).

• Education: Doctor of Philosophy (1982) from Yale University, and Bachelor of Arts (1976) from Dartmouth College.

Research Interests: Fried focuses on DNA repair, mutagenesis, and chemotherapy, with additional work on RNA splicing, PARP1, and transmembrane domain interactions in viruses like SARS-CoV and Hendra virus. His studies employ techniques such as analytical ultracentrifugation, electrophoretic mobility shift assays, and structural biology.

Recent Publications: His 2024 Scientific Reports article explores cooperative nucleic acid binding by PARP1, while 2018 works on nonribosomal peptides and viral fusion proteins highlight his interdisciplinary approach. Earlier studies (2015–2018) examine AGT cooperativity, DNA repair in telomeres, and paramyxovirus fusion domains.

Grants: Active grants include roles as PI for the Van Andel Institute (2022–2023) and CoI on NSF-funded projects (2020–2022) studying RNA splicing and PARP1. Past collaborations (2012–2014) focused on viral proteins and DNA repair.