
معرفی
Michael D. Lynch is the W. H. Gardner, Jr. Associate Professor of Biomedical Engineering at Duke University, affiliated with the Pratt School of Engineering. He also holds appointments in the Department of Chemistry (Trinity College of Arts & Sciences) and the Duke Initiative for Science & Society. His research focuses on genetically engineering microbes to produce valuable chemicals and therapeutics through dynamic metabolic control and synthetic biology approaches.
Education: M.D. (University of Colorado School of Medicine, 2007), Ph.D. (University of Colorado, Boulder, 2005).
Research interests include microbial strain engineering, bioprocess optimization, CRISPR-based technologies, and scalable production of biofuels/therapeutics. Recent work emphasizes protein purification methods (nanobodies, Griffithsin), two-stage microfermentation systems, and techno-economic analysis of bioprocesses. His grants include NIH-funded projects on biomolecular engineering training, CRISPR-enabled DNA synthesis, and sustainable production of energetic materials.
Professional activities include leading Duke's undergraduate iGEM team and developing open-source bioprocessing tools like BioSamplr. Teaching responsibilities span advanced biomedical engineering courses, independent research supervision, and interdisciplinary projects. Lynch's lab innovates in strain design, bioreactor automation, and cost-effective manufacturing strategies for industrial biotechnology.


