Michael Chappell

Professor Michael Chappell is a faculty member of the School of Engineering at the University of Warwick, where he has held academic roles since 1990. He leads the Systems and Information Discipline Stream and serves as the MEng Course Manager for all Engineering streams. His research focuses on mathematical modeling of biomedical, pharmacokinetic, and biological processes, emphasizing structural identifiability analysis, system dynamics, and nonlinear systems. He collaborates with academic, industrial, and hospital-based groups, securing funding from EPSRC, BBSRC, and MRC. Currently, he is Deputy Director of Warwick's Mathematics in Medicine Initiative (MiMI) and Co-director of the Centre for Medical Science and Technology.

Research interests include biomedical engineering, pharmacokinetics, systems biology, and control theory, with applications to drug development, medical technology, and disease modeling. Techniques such as computer algebra systems and robust simulation of stiff systems are central to his work. He also explores the interplay between theoretical models and experimental data in pharmacology and physiology.

• Key Projects/Grants:
• "Analyses to Improve Efficiency in Oncology Clinical Drug Development" (AstraZeneca, 2020–2024)
• "A sensorimotor PROsthesis for the upper LIMB (PROLIMB)" (EPSRC, 2020–2023)
• Co-founded the UK Quantitative and Systems Pharmacology Network (EPSRC, 2015–2018)

His 2001 Snell Premium award recognizes contributions to biomedical signal processing via wavelet analysis of heart rate variability for sleep apnoea detection. He advises students such as Edmond Watson and C. Thornton through collaborative studentships and maintains office hours every Friday from 10 am to 12 noon. His interdisciplinary work bridges engineering methodologies with medical and biological applications, promoting efficient translational research and reducing reliance on animal testing through quantitative systems toxicology.