معرفی
Dr Melpomeni (Melina) Kalofonou is an Advanced Research Fellow and Group Lead in Cancer Technology at the Centre for Bio-Inspired Technology (CBIT), Department of Electrical and Electronic Engineering, Imperial College London. She holds an adjunct role as Assistant Professor in Targeted Diagnostics and Therapeutics at Stony Brook University's Renaissance School of Medicine. Her work focuses on semiconductor-based systems for cancer diagnostics, integrating electrochemical sensors with molecular assays in Lab-on-Chip platforms.
Education:
- MEng in Electrical & Computer Engineering (University of Patras, 2007)
- MSc in Biomedical Engineering (Imperial College London, 2009)
- PhD in Electrical & Electronic Engineering (Imperial College London, 2013)
Research Interests: Development of Lab-on-Chip technologies for multi-cancer detection, epigenetic biomarker analysis via ISFET sensors, and machine learning-driven drug resistance prediction. Her projects emphasize affordable, accessible diagnostics for breast, colorectal, ovarian, and prostate cancers.
Articles Overview: Recent work highlights advancements in ISFET-based detection of genetic mutations (e.g., BRAF V600E, TP53 R248W), integration of machine learning for diagnostic algorithms, and innovations in liquid biopsy analysis. Key themes include improving clinical translation through interdisciplinary collaborations.
Affiliations & Grants: Leads Imperial's CRUK-funded multidisciplinary projects and EPSRC initiatives. Serves on the IEEE BioCAS Technical Committee and editorial boards of IEEE journals. Active in the CRUK Convergence Science Centre and Imperial's Cancer Research UK Centre.
Labs & Teams: Directs the Cancer Technology group within CBIT, fostering collaboration between electrical engineers and medical professionals. Supervises Masters’ students across Engineering and Medicine faculties.
