معرفی
Melanie Worley is an Assistant Professor in the Department of Biology at the University of Virginia. Her research focuses on understanding the molecular and cellular mechanisms of tissue regeneration in Drosophila melanogaster, particularly how cells coordinate regenerative processes after damage. She leads the Worley Lab, which employs experimental genetics, developmental biology, and single-cell transcriptomics to study gene regulatory networks involved in regeneration.
Education:
- B.S., Massachusetts Institute of Technology, 2006
- Ph.D., University of California, Berkeley, 2013
Research Interests:
Dr. Worley investigates regeneration mechanisms in Drosophila imaginal discs, exploring how cells maintain a pro-regenerative transcriptional program and coordinate re-patterning. Her lab uses innovative techniques like single-cell transcriptomics to dissect interactions between epithelial and myoblast cells. The goal is to uncover pathways applicable to human regenerative medicine.
Publications:
Her work includes studies on Ets21C's role in blastema cells, CtBP's regulation of growth pathways, and the development of TIE-DYE, a genetic marking system. Recent efforts emphasize spatiotemporal control of cell ablation in Drosophila.
Labs/Teams:
The Worley Lab collaborates on projects at the intersection of developmental biology and regenerative medicine. Visit her lab website for current projects and opportunities.
