Max Krummel

Max Krummel is a Professor at the University of California San Francisco, leading research on immune system dynamics and tumor microenvironment interactions. His work focuses on T cell signaling, imaging-based analysis of immune responses, and translational applications in cancer therapy. He has pioneered real-time imaging techniques and developed antibody therapies like ipilimumab for melanoma. Krummel's lab integrates fluorescent tagging, flow cytometry, and advanced imaging to study immune cell behavior in tissues such as lymph nodes, lungs, and tumors.

• Education:
  • B.S. in Biology and Chemistry, University of Illinois (1985-1989)
  • Ph.D. in Immunology, University of California, Berkeley (1989-1995)
  • Postdoctoral training at Walter and Eliza Hall Institute (Melbourne, 1996-1997) and Stanford University (1997-2001)
• Honors:
  • James Scholar (University of Illinois, 1986)
  • Juvenile Diabetes Foundation Postdoctoral Fellowship (1996-2000)
  • NIH NRSA Postdoctoral Fellowship (1997-2000)
  • Cancer Research Institute Investigator Award (2004-2007)

His research emphasizes understanding immune cell communication and stromal interactions in tumors, leveraging imaging tools to dissect complex cellular networks. Recent work includes studying CD206+ macrophage roles in antitumor immunity and developing models to track tumor-educated immune cells. Krummel has secured NIH grants totaling over $50M as Principal Investigator, focusing on tumor immunity, cytoskeletal regulation, and lung biology.

Publications highlight innovations in intravital imaging, immune archetyping for cancer classification, and metabolic reprogramming in immune cells. His lab collaborates widely, including the UCSF COMET Consortium for pandemic research and translational studies in lung repair.