معرفی
Maud Frieden is an Associate Professor at the Department of Cell Physiology and Metabolism, University of Geneva. Her lab focuses on skeletal muscle regeneration mechanisms using human stem cell models. Key research areas include muscle satellite cell activation, calcium signaling pathways, and the molecular basis of muscle diseases like myopathies.
Research Interests: Frieden’s work investigates how muscle stem cells (satellite cells) repair damaged muscle tissue. Recent projects explore store-operated calcium entry (SOCE) pathways in muscle differentiation and the role of mitochondrial dysfunction in muscle atrophy. Advanced in vitro models are used to study human myotube maturation and disease mechanisms.
Lab Team: Current members include PhD students Jessica Brunetti and Julie Perroud, postdoc Axel Tollance, and lab technician Olivier Dupont. The team collaborates with experts in proteomics (e.g., Eckhardt et al., 2023) and cardiac physiology (Rusiecka et al., 2023).
Publications: Recent work highlights ER stress-IRE1 interactions in muscle regeneration (Carreras Sureda et al., 2023) and TRPC channel roles in myogenesis (Antigny et al., 2013-2022). Over 30 peer-reviewed articles span muscle biology, calcium signaling, and stem cell research.
