Matthew Spitzer

Matthew Spitzer is a researcher at the University of California San Francisco (UCSF), leading the Spitzer Lab which focuses on understanding immune system coordination in tumor immunology. His work integrates experimental immunology, cancer biology, and computation to develop curative immune responses against cancer. He has held roles as Principal Investigator and Co-Principal Investigator on NIH-funded grants, including projects on modeling immune responses to cancer and characterizing bone marrow microenvironments.

Education: B.S. in Biology from Georgetown University (2011); Ph.D. in Immunology from Stanford University (2016). Awards include the NIH Early Independence Award, Sandler Faculty Fellow distinction, and multiple honors for academic excellence and research, including the Howard Hughes Undergraduate Research Scholarship.

Research interests emphasize tumor immunity, immunotherapy resistance mechanisms, and systemic immune dynamics. His lab’s recent work explores CAR-T cell metabolism, immune checkpoint inhibitors, and intercellular interactions in cancer contexts. Over 30 publications highlight his contributions to immunology and oncology, with a focus on translational applications.

Grants and Collaborations: Multiple NIH awards (DP5OD023056, R21AG057224) and collaborations with institutions like Stanford and UCSF. Current projects include developing novel immunotherapy strategies and understanding tumor microenvironment adaptations.

Labs/Teams: Spitzer Lab at UCSF, collaborating with experts in immunology, oncology, and computational biology to advance precision cancer immunotherapy.