معرفی
Matthew S Kayser is the Karl E. Rickels Associate Professor of Psychiatry II at the Perelman School of Medicine, University of Pennsylvania. He serves as an Attending Psychiatrist in the Department of Psychiatry, Associate Program Director for the Psychiatry Residency, and Training Director for the NIMH R25 program, with clinical expertise in sleep and mental health.
His educational background includes:
- ScB in Neuroscience from Brown University (2000)
- MD and PhD in Neuroscience from the University of Pennsylvania School of Medicine (2009)
Dr. Kayser's research investigates how neural circuits generate complex behaviors and how their dysfunction causes mental illness, with a focus on sleep's role in brain development and neuropsychiatric disorders. His lab employs Drosophila melanogaster genetics to study sleep's impact on synaptic formation, brain circuit sculpting, and links to conditions like autism and neurodegeneration.
Recent publications (2021-2024) reveal consistent themes: genetic regulation of sleep homeostasis (e.g., TDP-43, Neurofibromin 1), developmental sleep mechanisms, and clinical insomnia treatments. His work bridges Drosophila neurogenetics with human psychiatric conditions through molecular, behavioral, and clinical approaches.
Dr. Kayser has not listed any specific scientific awards in the provided information.
As Associate Program Director for Psychiatry Residency and NIMH R25 Training Director, he leads physician-scientist training with grants supporting sleep and chronobiology research. His lab develops neurogenetic approaches to connect sleep abnormalities with psychiatric pathogenesis.
The Kayser Lab (kayserlab.com), part of the Chronobiology and Sleep Institute, utilizes Drosophila genetics, molecular biology, and imaging to investigate how sleep shapes neural circuits during development and contributes to mental illness.
