Matthew Kudek

Matthew Kudek, MD is an Assistant Professor at the Medical College of Wisconsin, affiliated with the Departments of Pediatrics (Hematology/Oncology/BMT) and Microbiology & Immunology. His work focuses on understanding immune responses in cancer and immunotherapy, particularly graft-versus-host disease (GVHD) following allogeneic hematopoietic stem cell transplantation. He employs mouse models to study signaling mechanisms between innate and adaptive immune components in GVHD, aiming to design novel immunotherapies.

Dr. Kudek earned his MD from the University of Wisconsin-Madison in 2014. His research integrates techniques like single-cell analysis, flow cytometry, and transcriptome analysis to investigate cellular interactions in disease contexts such as viral infections and cancer. His clinical expertise includes pediatric oncology, precision medicine, and bone marrow transplantation.

Key research themes include T-lymphocyte differentiation, cytokine regulation (e.g., IL-34, IL-21), and the role of transcription factors like BATF in immune homeostasis. His work has explored age-related changes in immune responses to influenza and mechanisms of CD8+ T cell effector function in chronic infections/cancer.

Publications highlight translational research in GVHD mitigation, tumor immunology, and survivorship care for childhood cancer patients. Methodologies span adoptive transfer, histology, and genetic/transduction-based approaches. While no awards are explicitly listed, his work aligns with prestigious topics in immunology and oncology research.