Matthew Dalva

Matthew Dalva is a Professor of Cell and Molecular Biology at Tulane University, holding the Phyllis M Taylor Presidential Chair and serving as Director of the Tulane Brain Institute. He earned his Ph.D. in Neurobiology from Duke University in 1996. His research focuses on synaptic development and function, particularly mechanisms governing synapse formation, NMDA receptor regulation, and synaptic nano-architecture. The Dalva Lab employs advanced techniques like super-resolution microscopy (STED) and genetically encoded kinase activity reporters to study synapses in vivo.

Research interests include synaptic plasticity, Eph/ephrin signaling pathways, and pain mechanisms. His team explores how synaptic structures adapt to activity and injury, with implications for neurological diseases like ALS and chronic pain. The lab is part of the School of Science & Engineering and collaborates on multidisciplinary projects combining molecular biology, biochemistry, and microscopy.

Recent work highlights the role of EphB2 and ephrin-B2 in pain plasticity, synaptic module organization, and spinal cord neuroprotection. Open positions exist for postdoctoral researchers and lab managers skilled in molecular biology and imaging. Tulane Brain Institute affiliations enhance translational research efforts, emphasizing innovation in synaptic tools and technology.