Amparo Acker-Palmer

Amparo Acker-Palmer is a Professor at the Institute of Cell Biology and Neuroscience, part of the Cluster of Excellence Macromolecular Complexes (CEF) at Goethe University Frankfurt in Germany. Her laboratory investigates molecular mechanisms of cell-cell communication through ephrin/Eph receptor systems in neuronal and vascular networks.

Research Focus

Her group studies:

• Crosstalk between angiogenic/neurotrophic factors and ephrin signaling
• Molecular pathways in spine morphogenesis, synaptic plasticity, and dendritogenesis
• Ephrin-mediated neuronal migration during cortical development and adult neurogenesis
• Neuro-vascular interactions in development and disease contexts

Methodologies

• Tandem Affinity Purification (TAP) proteomics in mammalian systems
• Primary neuronal/endothelial cell cultures (rat/mouse)
• Transgenic mouse models and time-lapse imaging
• Biochemical assays (kinase/IP/IF) and migration/adhesion analyses

Her publications demonstrate consistent focus on Eph/ephrin signaling in neurodevelopment, plasticity, and angiogenesis across high-impact journals including Nature, Science, and Cell Reports.