معرفی
Matteo Borgini is an Assistant Professor in Medicinal Chemistry at Augusta University's Department of Chemistry and Biochemistry within the College of Science and Mathematics. His research focuses on developing novel covalent inhibitors and targeting transcription factors like Nrf2 for drug discovery.
- Education: MS and PhD in Chemistry from University of Siena (2020)
- Research Areas: Covalent inhibitors, undruggable targets, synthetic organic chemistry, Nrf2 pathway modulation
Recent Research Highlights: Dr. Borgini's work explores strain-release transformations for acrylamide-type warheads, enabling substrate-specific covalent inhibitors. His lab also investigates Nrf2 regulation in cancer and neurodegenerative diseases, aiming to elucidate downstream pathways and create first-in-class therapeutics.
Scientific Contributions: Recent publications focus on C-H functionalization, 13C-labeled amino acids, and mitochondrial-targeted prodrugs. His team leverages transition-metal catalysis and stereoselective synthesis to advance medicinal chemistry tools.
- Awards: Poster Award (UPMC Hillman Cancer Center, 2022), COST Travel Fellowships (2019), Doctoral Fellowship (UNAVIR, 2016)
