معرفی
Mati Karelson is a Full Professor at the University of Tartu's Institute of Chemistry in Estonia, where he has maintained a continuous academic appointment since September 1992. With an educational background in Chemistry from Tartu State University (1992-1995), he has established himself as a leading researcher in computational chemistry and drug design.
Professor Karelson's research spans multiple disciplines with a strong focus on computational approaches to drug discovery. His work prominently features:
- Quantitative Structure-Activity Relationship (QSAR) modeling
- Molecular docking and virtual screening
- Epitranscriptomics, particularly RNA methylation (m6A)
- Neurodegenerative disease research, especially Parkinson's disease
- Antiviral drug development targeting HIV and flaviviruses
His recent publications (2023-2025) demonstrate a strong emphasis on the intersection of computational chemistry and biological applications, particularly in developing small molecule modulators of RNA methylation pathways and their therapeutic potential for neurological disorders and viral infections. Professor Karelson has published 238 papers with over 44,875 reads and 13,947 citations, reflecting significant impact in his field.
His research collaborations span multiple institutions internationally, working with experimental biologists to validate computational predictions. The interdisciplinary nature of his work bridges computational chemistry with neuroscience, virology, and molecular biology, creating a robust research program with translational potential.
