Mathilde VAN der HENST

Mathilde VAN der HENST is an active researcher specializing in bacterial pathogenesis with a focus on Brucella abortus. Her research examines the complex cell cycle regulation and intracellular growth mechanisms of this pathogenic bacterium. She completed her doctoral studies in 2019 with a thesis on the replication and role of (p)ppGpp in Brucella abortus.

Her research interests span multiple interconnected domains within microbiology and immunology. She investigates how Brucella manipulates host cell processes, particularly focusing on macrophage interactions and cell cycle progression. Her work combines molecular genetics, bacterial physiology, and host-pathogen interaction studies to understand the fundamental mechanisms of bacterial pathogenesis.

Analysis of her recent publications (2018-2022) reveals a strong focus on cell cycle regulation in Brucella abortus, with particular attention to two-component regulatory systems, metabolic pathway coordination, and the role of (p)ppGpp in intracellular survival. Her research consistently connects bacterial cell cycle control with virulence mechanisms and host adaptation.

As Principal Investigator on the project 'Study of the replication control and polarity in Brucella abortus' (2018-2019), she demonstrated leadership in her field. Her collaborative network includes researchers across multiple institutions, as evidenced by her co-authorships with scientists from various backgrounds.

Her research operates at the intersection of microbiology, cell biology, and immunology, with significant implications for understanding bacterial pathogenesis and developing potential therapeutic interventions against intracellular pathogens.